Right Ventricular Dysfunction During Endurance Exercise as Determined by Pressure-Volume Analysis
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Updated: Aug 21, 2025

Cardiac Pressure-Volume Loop Analysis Using Conductance Catheters in Mice
Published on: September 17, 2015
Justin A Edward1, Lukasz P Cerbin1, Daniel W Groves1,2
1Department of Medicine-Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Abstract:
A 37-year-old athlete completed invasive endurance (90 km) bicycle exercise testing for right ventricular pressure-volume analysis. Increased right ventricular afterload caused declines in ventricular-arterial coupling and cardiac output, causing increased arteriovenous oxygen difference to maintain oxygen uptake. These findings demonstrate effects of changes in right ventricular performance on exercise capacity. (Level of Difficulty: Intermediate.).
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