Related Experiment Video
Updated: Aug 21, 2025
06:38
Induction of Ocular Surface Inflammation and Collection of Involved Tissues
Published on: August 4, 2022
2.4K
Glaucoma and Ocular Surface Disease: More than Meets the Eye
Gavin Li1, Esen Karamursel Akpek2, Sumayya Ahmad1
1Department of Ophthalmology at the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Clinical Ophthalmology (Auckland, N.Z.)
|November 17, 2022
Summary
Glaucoma treatment with eye drops can harm the ocular surface over time, impacting patient quality of life and adherence. This review examines glaucoma and ocular surface disease links, drop effects, and management strategies.
Area of Science:
- Ophthalmology
- Ocular Surface Disease
- Glaucoma
Background:
- Topical antihypertensive medications are standard glaucoma treatment.
- Long-term ocular surface effects of these medications are not well understood.
- Ocular surface disease significantly impacts patient quality of life and treatment adherence.
Purpose of the Study:
- To review the association between ocular surface disease and glaucoma.
- To examine the impact of different classes of topical glaucoma drops on the ocular surface.
- To discuss management strategies for ocular surface disease in glaucoma patients.
Main Methods:
- Nonsystematic review of literature.
- Literature search conducted in April 2022.
- Focused on the relationship between glaucoma and ocular surface disease, effects of topical glaucoma medications, and treatment options.
Main Results:
- Topical glaucoma medications can negatively affect the ocular surface.
- Understanding these effects is crucial for long-term patient management.
- Various treatment strategies exist for ocular surface disease in glaucoma patients.
Conclusions:
- The long-term use of topical glaucoma medications necessitates careful monitoring of ocular surface health.
- Addressing ocular surface disease is vital for improving patient adherence and quality of life.
- Minimizing the burden of topical medications may involve exploring alternative treatments.
Related Concept Videos
01:25Glaucoma: Overview
689
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
689
01:27Open Angle Glaucoma: Treatment
521
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
521
01:28Angle Closure Glaucoma: Treatment
617
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
617
01:22Photoreceptors and Visual Pathways
6.2K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.2K
01:17Accessory Structures of the Eye
1.7K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.7K