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Updated: Aug 20, 2025

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
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Delivery of Radioiodine Ablation in a Patient with End-Stage Renal Disease
Andrew T Bussey1, Aung Tin2, Neil Hoye3
1Department of Nuclear Medicine, South Tees Hospitals NHS Foundation Trust, Middlesbrough, United Kingdom.
Abstract:
This case presents a pragmatic approach to the management of a radioiodine remnant ablation patient on hemodialysis which required no pretherapeutic dosimetric measurements. Pretreatment radiation dose modeling was performed using literature values for radioiodine hemodialysis extraction efficacies to determine a safe treatment regimen including adjustment of the administered activity and hemodialysis frequency. The pretreatment modeling was subsequently verified using external and blood radiation monitoring during treatment.
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