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Related Experiment Video

Updated: Aug 20, 2025

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
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Frailty: A Multidimensional Biopsychosocial Syndrome.

Carl I Cohen1, Rivka Benyaminov1, Manumar Rahman1

  • 1SUNY Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.

The Medical Clinics of North America
|November 19, 2022
PubMed
Summary
This summary is machine-generated.

Frailty is now understood as a complex, multidimensional biopsychosocial syndrome. This updated view incorporates physical, cognitive, social, and psychological aspects, broadening research and clinical practice.

Keywords:
Cognitive frailtyFrailtyPsychological frailtySocial frailty

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Area of Science:

  • Gerontology
  • Public Health
  • Biopsychosocial Medicine

Background:

  • Frailty conceptualization has evolved from a purely physical decline to a complex, multidimensional biopsychosocial syndrome.
  • This evolution necessitates a broader, interdisciplinary approach involving social and behavioral scientists and diverse clinical specialties.

Purpose of the Study:

  • To provide an updated overview of the conceptual changes in frailty research.
  • To examine emerging definitions, assessment tools, epidemiology, pathogenesis, risk factors, and treatment frameworks for frailty domains.

Main Methods:

  • Literature review and synthesis of current research on frailty.
  • Analysis of emerging definitions and diagnostic/assessment tools across physical, cognitive, social, and psychological domains.
  • Examination of epidemiological data, risk factors, pathogenesis, and intervention strategies.

Main Results:

  • Frailty is increasingly recognized as encompassing physical, cognitive, social, and psychological dimensions.
  • Diverse assessment tools are emerging for each frailty domain.
  • Epidemiology, risk factors, and treatment strategies are being investigated across these multiple domains.

Conclusions:

  • The multidimensional biopsychosocial model of frailty requires integrated research and clinical strategies.
  • Further research is needed to address unresolved issues and refine prevention and treatment approaches.
  • Understanding frailty as a complex syndrome enhances its management and impacts public health initiatives.