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Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

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Pathology Mimicking Orofacial Pain.

Shaiba Sandhu¹, Shruti Handa¹

¹Division of Orofacial Pain, Oral and Maxillofacial Surgery, Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA; Harvard School of Dental Medicine, Boston, MA, USA.

Dental Clinics of North America

|November 20, 2022

Summary

A benign parotid gland tumor, pleomorphic adenoma, caused new-onset orofacial pain and swelling in a 64-year-old woman. Prompt diagnosis and surgical removal via total parotidectomy resolved the symptoms.

Keywords:

Facial swelling Orofacial pain Parotid gland swelling Pleomorphic adenoma Salivary gland tumors

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Area of Science:

Oral and Maxillofacial Surgery
Oncology
Diagnostic Imaging

Background:

Pleomorphic adenoma is the most common benign tumor of the salivary glands.
Orofacial pain can arise from various pathologies, necessitating thorough differential diagnosis.
Facial swelling and fullness are potential indicators of underlying neoplastic processes.

Observation:

A 64-year-old woman presented with new-onset pain superimposed on a pre-existing area of right mandibular fullness.
Clinical examination, Magnetic Resonance Imaging (MRI), and fine-needle aspiration cytology were utilized for diagnosis.

Findings:

The diagnostic workup confirmed a benign parotid gland tumor, specifically a pleomorphic adenoma.
The patient underwent total parotidectomy for complete tumor removal.

Implications:

Oral health care providers must consider benign parotid gland tumors in the differential diagnosis of orofacial pain.
Persistent or enlarging facial swelling/fullness should be recognized as red flags warranting comprehensive evaluation.
Early detection and surgical management of pleomorphic adenoma can lead to favorable patient outcomes.