Related Experiment Video
Updated: Aug 20, 2025

A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy
Published on: September 13, 2022
Computed tomography-guided percutaneous cholecystostomy: a single institution's 6-year experience
Ioanna Konstantina Sgantzou1, Athina A Samara2, Antonis Adamou1
1Department of Radiology (Ioanna Konstantina Sgantzou, Antonis Adamou, Georgios Karagiorgas, Ioannis Ioannidis, Marianna Vlychou, Christos Rountas).
This study examined the outcomes of CT-guided percutaneous cholecystostomy in patients at high surgical risk. Researchers reviewed records from 86 patients who underwent the procedure between 2015 and 2020. The main outcomes were 7- and 30-day mortality rates. The 7-day mortality rate was 16.3%, and the 30-day rate was 22.1%. ICU admission was strongly linked to higher mortality, while other factors like age, diagnosis, and catheter size were not. The study suggests that CT-guided PC is a safe alternative to surgery for high-risk patients. These findings support the use of imaging-guided procedures in emergency care settings.
Area of Science:
- Interventional radiology techniques in acute care
- Surgical risk stratification in emergency medicine
- Computed tomography applications in procedural guidance
Background:
High-risk surgical patients often face limited treatment options for acute gallbladder conditions. Standard care typically involves surgical removal of the gallbladder. However, patients with significant comorbidities may not tolerate surgery well. Prior research has shown that percutaneous cholecystostomy can serve as an alternative. This gap motivated a closer look at outcomes when using computed tomography guidance. No prior work had resolved whether CT-guided procedures could reliably reduce mortality in high-risk groups. Understanding the role of imaging modalities is essential for refining treatment algorithms. The need to assess procedural safety in vulnerable populations remains unmet. This paper contributes by focusing on a specific imaging-guided approach. The study addresses a critical need in emergency surgical decision-making.
Purpose Of The Study:
The study aimed to assess the safety and outcomes of CT-guided percutaneous cholecystostomy in high-risk patients. Researchers focused on mortality rates as the primary outcome measure. They examined 7- and 30-day mortality following the procedure. The motivation stemmed from a need to evaluate non-surgical alternatives for at-risk patients. This approach could offer a safer option for those unsuitable for surgery. The study also investigated factors that might influence mortality outcomes. The goal was to determine if CT-guided PC could provide acceptable survival rates. This work contributes to the growing field of interventional emergency care.
Main Methods:
The study reviewed medical and imaging records from a single institution over six years. Researchers included all consecutive patients who underwent CT-guided percutaneous cholecystostomy. Participants were adults with confirmed indications for the procedure. The primary outcomes were 7- and 30-day mortality rates. Secondary variables included ICU admission and other clinical parameters. Data collection focused on patients deemed high surgical risk. The analysis included 86 patients with various gallbladder pathologies. The study design allowed for a detailed review of procedural outcomes.
Main Results:
The 7-day mortality rate was 16.3% among the 86 patients studied. The 30-day mortality rate rose to 22.1%. ICU admission was significantly associated with higher mortality (P<0.05). Age, sex, diagnosis, and catheter size did not show significant associations. The most common diagnosis was acute cholecystitis (58.1%). Other conditions included cholangitis, empyema, and hydrops. Mortality was not linked to catheter diameter or hospital stay duration. These findings suggest ICU status is a key factor in procedural outcomes.
Conclusions:
The study found that CT-guided percutaneous cholecystostomy is a viable option for high-risk patients. Mortality rates were acceptable compared to surgical alternatives. ICU admission was a significant predictor of mortality. Other clinical variables did not impact outcomes significantly. The procedure provides a safe alternative when surgery is contraindicated. The results support the use of imaging-guided interventions in this population. The findings align with prior research on non-surgical treatments. These conclusions suggest a role for CT-guided PC in emergency care.
Frequently Asked Questions
The 7-day mortality rate was 16.3%, and the 30-day rate was 22.1%.
Hospitalization in the intensive care unit was significantly associated with higher mortality (P<0.05).
CT guidance was selected for its precision in high-risk patients, where surgical options are limited.
ICU admission was a significant predictor of mortality, suggesting higher baseline illness severity.
No significant association was found between catheter diameter and mortality outcomes.
It supports CT-guided PC as a safe alternative for high-risk patients who cannot undergo surgery.
