Related Experiment Video
Updated: Aug 20, 2025

Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles
Published on: August 17, 2022
Misinformation versus Facts: Understanding the Influence of News regarding COVID-19 Vaccines on Vaccine Uptake
Hanjia Lyu1, Zihe Zheng2, Jiebo Luo1
1Department of Computer Science, University of Rochester, Rochester, USA.
Background:
There is a lot of fact-based information and misinformation in the online discourses and discussions about the COVID-19 vaccines.
Method:
Using a sample of nearly four million geotagged English tweets and the data from the CDC COVID Data Tracker, we conducted the Fama-MacBeth regression with the Newey-West adjustment to understand the influence of both misinformation and fact-based news on Twitter on the COVID-19 vaccine uptake in the US from April 19 when US adults were vaccine eligible to June 30, 2021, after controlling state-level factors such as demographics, education, and the pandemic severity. We identified the tweets related to either misinformation or fact-based news by analyzing the URLs.
Results:
One percent increase in fact-related Twitter users is associated with an approximately 0.87 decrease (B = -0.87, SE = 0.25, and p < .001) in the number of daily new vaccinated people per hundred. No significant relationship was found between the percentage of fake-news-related users and the vaccination rate.
Conclusion:
The negative association between the percentage of fact-related users and the vaccination rate might be due to a combination of a larger user-level influence and the negative impact of online social endorsement on vaccination intent.
More Related Videos
Related Concept Videos
Vaccinations
Bias in Epidemiological Studies
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Confounding in Epidemiological Studies
The Availability Heuristic
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

