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Published on: August 4, 2023
Hereditary Angioedema During Pregnancy: Considerations in Management
1Division of Rheumatology, Allergy & Immunology, Department of Medicine, University of California - San Diego, 8899 University Center Lane, Suite 230, La Jolla, CA 92122, USA.
Abstract:
In recent years, hereditary angioedema (HAE) management has substantially advanced but also become more complex with additional therapeutic options. Pregnancy significantly influences the clinical symptoms of HAE in many women because of estrogen effects or other physiologic factors, and also introduces important safety concerns related to HAE medications. Management of HAE during pregnancy requires clinicians to be familiar with the potential clinical course, triggers, and recommended treatment strategies to provide guidance and optimal medical management to women and families affected by the condition. This review provides an overview of data, considerations, and recommendations related to HAE and pregnancy.
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