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Design and Implementation of Taizhou Integrated Prostate Screening
Fei-Ping Li1, Mei-Xian Zhang2, Li-Jun Wang1
1Department of Urology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China.
American Journal of Men'S Health
|November 22, 2022
Summary
This prostate cancer screening study in China found an 11.5% prevalence of elevated PSA in men over 50. Older age significantly increased the risk of elevated PSA, highlighting the need for early detection programs.
Area of Science:
- Urology
- Public Health
- Epidemiology
Background:
- Prostate cancer screening is crucial for early detection in aging male populations.
- Understanding the prevalence and risk factors in specific geographic regions is essential for targeted public health initiatives.
Purpose of the Study:
- To assess prostate cancer morbidity and associated factors in men aged ≥50 years in Taizhou, China.
- To evaluate the effectiveness of a community-based screening program using serum prostate-specific antigen (PSA) levels.
Main Methods:
- A population-based observational study involving a pilot census of men aged ≥50 years in Luqiao District, Taizhou.
- Data collection included interviewer-administered questionnaires on demographics and environmental factors, alongside serum PSA measurements.
- 1,806 participants completed the study.
Main Results:
- The overall prevalence of PSA ≥4 ng/mL was 11.5%, categorized into low (9.2%), moderate (1.7%), and high (0.6%) risk groups.
- Older age groups showed significantly higher risks: 2.7-fold for 60-69, 4.2-fold for 70-79, and 6.5-fold for ≥80 years compared to 50-59 year olds (p < .001).
- Prostate cancer was diagnosed in 18 patients, with 11 undergoing radical surgery.
Conclusions:
- The community-based PSA screening program demonstrated success in the early detection of prostate cancer among men aged ≥50 years.
- Early screening and timely clinical management are vital for improving outcomes in this demographic.
- Findings underscore the importance of targeted screening programs in specific populations to address prostate cancer burden.
