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2D MXene-Based Biosensing: A Review.

Umay Amara1, Iftikhar Hussain2, Muhmmad Ahmad2

  • 1Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Small (Weinheim an Der Bergstrasse, Germany)
|November 22, 2022
PubMed
Summary
This summary is machine-generated.

MXene, a 2D material, shows great promise for biosensing due to its conductivity and biocompatibility. This review details MXene

Keywords:
MXenesbiosensingelectrochemicalmechanismsoperating principleoptical

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • MXene is a 2D material with excellent metallic conductivity, optical absorbance, and mechanical stability.
  • Its properties, including a high heterogeneous electron transfer rate and redox capability, make it suitable for biosensing.
  • MXene's hydrophilic nature, biocompatibility, antifouling, and anti-toxicity properties enable in vitro and in vivo applications.

Purpose of the Study:

  • To comprehensively review the concept, operating principles, mechanisms, and properties of MXene for biosensing.
  • To assess breakthroughs in MXene fabrication and conjugation strategies for biosensor development.
  • To summarize current challenges and suggest future directions for MXene-based biosensors.

Main Methods:

  • Literature review of MXene fabrication and conjugation strategies.
  • Analysis of MXene properties relevant to biosensing.
  • Compilation of existing research on MXene-based electrochemical and optical biosensors.

Main Results:

  • MXene exhibits unique properties ideal for electrochemical and optical biosensing.
  • Various fabrication and conjugation strategies have been developed to enhance MXene performance.
  • MXene-based biosensors demonstrate significant potential for diverse analytical applications.

Conclusions:

  • MXene is a highly promising 2D material for advanced biosensing applications.
  • Further research into fabrication and conjugation is crucial for optimizing MXene-based biosensors.
  • MXene bioassays offer new opportunities for translational applications in diagnostics and monitoring.