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Correlation Between Quantitative Value of Endolymphatic Hydrops and Hearing Threshold Using Magnetic Resonance
Weidong Zhang1, Jiapei Xie1, Songbai Li2
1Department of Medical Imaging, Zhengzhou University People's Hospital & Henan Provincial People's Hospital, Zhengzhou, China.
The Annals of Otology, Rhinology, and Laryngology
|November 22, 2022
Summary
Quantitative assessment of endolymphatic hydrops using 3D-FLAIR MRI correlates with hearing loss in Meniere
Area of Science:
- Otolaryngology
- Radiology
- Medical Imaging
Background:
- Meniere's disease is characterized by endolymphatic hydrops, an excess of fluid in the inner ear.
- The relationship between the severity of endolymphatic hydrops and hearing loss requires further investigation.
Purpose of the Study:
- To investigate the correlation between the quantitative value of endolymphatic hydrops and hearing thresholds in patients with unilateral Meniere's disease.
Main Methods:
- A prospective study involving 40 patients with unilateral Meniere's disease.
- Pure tone audiometry was used to assess hearing thresholds (low, middle, high).
- 3D-FLAIR MRI with gadoterate meglumine was used to quantify cochlear and vestibular endolymphatic hydrops.
Main Results:
- All patients exhibited endolymphatic hydrops.
- A significant positive correlation was found between cochlear hydrops and low/middle-tone hearing thresholds (r=0.581, r=0.610).
- Vestibular hydrops showed a stronger correlation with low-tone hearing thresholds (r=0.727) and moderate correlation with middle-tone thresholds (r=0.569).
Conclusions:
- 3D-FLAIR MRI effectively visualizes and quantifies endolymphatic hydrops in Meniere's disease.
- Low and middle-tone hearing thresholds can assist in the clinical evaluation of endolymphatic hydrops, supporting clinical symptoms.
