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Distinct Spinal Dysraphisms Arising from Each Hemicord of Type I Split Cord Malformation - A Rare Coexistence
Lavlesh Rathore1, Debabrata Sahana1, Sanjeev Kumar1
1Department of Neurosurgery, DKS Post Graduate Institute and Research Centre, Raipur, Chhattisgarh, India.
Insights
This report details a rare case of Type I split cord malformation in an infant, presenting complex spinal cord and Chiari malformations. Genetic research into posterior neuropore defects may explain this complex congenital anomaly.
Area of Science:
- Pediatric Neurology
- Developmental Biology
- Clinical Case Reports
Background:
- Split cord malformation (SCM) is a rare congenital anomaly of the spinal cord.
- Complex presentations of SCM, especially with concurrent Chiari malformations, pose diagnostic and etiological challenges.
- Existing embryological theories inadequately explain simultaneous, complex spinal defects at a single level.
Abstract:
In this report, we describe a 6-month-old child having Type I split cord malformation (SCM), associated with meningomyelocele of one hemicord and lipomeningomyelocele of other hemicord at the same level along with Type II Chiari malformation. The classical embryological theories on split cord malformation and neurulation defect do not clearly explain such a complex entity at one level. The new research on the genetic association of posterior neuropore defect opens a new horizon of research on such genesis.
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