Related Experiment Video
Updated: Aug 20, 2025
03:49
Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
Published on: September 20, 2018
19.3K
Perianal Paget's disease
Pilar Navajas Hernández1, Teresa Valdés Delgado1, Jesús Machuca Aguado2
1Aparato Digestivo, Hospital Universitario Virgen Macarena, España.
Revista Espanola De Enfermedades Digestivas
|November 22, 2022
Summary
Extramammary Paget's disease (EMPD) is rare and challenging to diagnose. This case highlights the importance of biopsy in identifying Paget cells in anal and gluteal lesions.
Area of Science:
- Dermatology
- Oncology
Background:
- Extramammary Paget's disease (EMPD) is an uncommon intraepithelial malignancy.
- Distinguishing primary EMPD from secondary involvement is critical for appropriate management.
Observation:
- An 85-year-old male presented with an erythematous plaque in the anal and gluteal region.
- The lesion's location and appearance prompted further investigation.
Findings:
- A biopsy confirmed the presence of Paget cells within the plaque.
- This histological finding is diagnostic of Paget's disease.
Implications:
- Early and accurate diagnosis of EMPD is crucial for patient outcomes.
- This case underscores the need for vigilance in evaluating anal and gluteal skin lesions.
Related Concept Videos
01:25Assessment of the Rectum and Anus
345
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
345
01:21Inflammatory Bowel Disease V: Surgical Management
190
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
190
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
24
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
24
01:30Peripheral Artery Disease I: Introduction
22
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
22
01:26Peripheral Artery Disease IV: Nursing Management
22
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
22
01:22Appendicitis-I: Introduction
405
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
405