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Lights on for Autism: Exploring Photobiomodulation as an Effective Therapeutic Option
Catherine Hamilton1, Ann Liebert2,3, Vincent Pang3
1WellRed Pty Ltd., Launceston, TAS 7250, Australia.
Neurology International
|November 22, 2022
Summary
Photobiomodulation, using red to near-infrared light, shows promise for treating autism. This therapy may improve neuronal function, reduce inflammation, and positively impact the gut microbiome in individuals with autism spectrum disorder.
Area of Science:
- Neuroscience
- Gastroenterology
- Biomedical Engineering
Background:
- Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social-communication deficits and restricted, repetitive behaviors.
- Underlying ASD pathology includes altered brain connectivity, neuronal dysfunction, inflammation, and gut microbiome dysbiosis.
- Current treatment options for ASD are limited, necessitating novel therapeutic approaches.
Purpose of the Study:
- To review the potential of photobiomodulation (PBM) as a novel therapeutic strategy for autism.
- To evaluate PBM's efficacy in addressing core autism-related neuropathological and physiological changes.
- To highlight PBM as a promising avenue for future autism research and treatment development.
Main Methods:
- Review of existing literature on photobiomodulation (PBM) and its effects on neurological and physiological conditions.
- Analysis of PBM's impact on neuronal connectivity, survival, inflammation, and gut microbiome composition.
- Synthesis of evidence supporting PBM's therapeutic potential for autism spectrum disorder.
Main Results:
- Photobiomodulation has demonstrated positive effects on neuronal connectivity and survival in various conditions.
- PBM can modulate inflammatory processes and gliosis, which are implicated in autism.
- Emerging evidence suggests PBM may influence the gut microbiome, a factor linked to autism.
Conclusions:
- Photobiomodulation presents a potential non-invasive treatment for autism by targeting key pathological mechanisms.
- PBM's ability to improve neuronal function, reduce inflammation, and influence the microbiome warrants further investigation for autism treatment.
- Further clinical trials are essential to establish the safety and efficacy of photobiomodulation for individuals with autism spectrum disorder.
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