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Learn-confirm in model-informed drug development: Assessing an immunogenicity quantitative systems pharmacology

Linnea C Franssen1, Maciej J Swat2, Andrzej M Kierzek2,3

  • 1Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Basel, Switzerland.

CPT: Pharmacometrics & Systems Pharmacology
|November 23, 2022
PubMed
Summary

Predicting immunogenicity of therapeutic proteins is challenging. The Immunogenicity Simulator, developed using trial data, shows credibility for assessing drug development risks.

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