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BioByGANS: biomedical named entity recognition by fusing contextual and syntactic features through graph attention

Xiangwen Zheng1, Haijian Du1, Xiaowei Luo1

  • 1Academy of Military Medical Sciences, Beijing, 100039, China.

BMC Bioinformatics
|November 24, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces BioByGANS, a novel model for biomedical named entity recognition (BioNER) that integrates semantic and syntactic features. BioByGANS outperforms existing methods by treating BioNER as a node classification problem using graph attention networks.

Keywords:
BioBERTBiomedical named entity recognitionContextual featuresGraph attention networkSpaCySyntactic featuresText mining

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Area of Science:

  • Biomedical text mining
  • Natural Language Processing
  • Bioinformatics

Background:

  • Biomedical named entity recognition (BioNER) is crucial for extracting knowledge from unstructured biomedical texts.
  • Current BioNER models often use deep neural networks but underutilize sentence syntactic features.
  • Integrating semantic and syntactic features is essential for improving BioNER performance.

Purpose of the Study:

  • To propose a novel BioNER model that effectively integrates semantic and syntactic features.
  • To address the limitations of existing models in utilizing sentence dependencies and topology.
  • To improve the accuracy and efficiency of biomedical knowledge extraction.

Main Methods:

  • Developed BioByGANS (BioBERT/SpaCy-Graph Attention Network-Softmax) model.
  • Formulated BioNER as a node classification problem using graph representations of sentences.
  • Utilized BioBERT for contextual features and SpaCy for syntactic features (POS, dependencies, topology).
  • Employed a Graph Attention Network (GAT) to fuse contextual and syntactic information.

Main Results:

  • BioByGANS achieved state-of-the-art performance on 8 benchmark datasets.
  • Achieved high F1-scores across datasets, including BC2GM (85.15%), JNLPBA (78.16%), and BC4CHEMD (92.97%).
  • Demonstrated superior performance compared to existing BioNER methods.

Conclusions:

  • The proposed BioByGANS model significantly improves BioNER performance.
  • Formulating BioNER as a node classification task with graph attention networks is effective.
  • Integrating syntactic features enhances the model's ability to capture linguistic nuances.