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Updated: Aug 20, 2025

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
In-hospital complications associated with total artificial heart implantation in the United States between 2004 to
Ahmed K Pasha1, Justin Z Lee2, Hem Desai3
1United Health Services Wilson Hospital in Johnson City NY, USA.
Insights
Total artificial heart (TAH) use has risen in the US. This study found significant complications and mortality rates associated with TAH implants, highlighting the risks of this life-saving device.
Area of Science:
- Cardiovascular Surgery
- Medical Device Technology
- Health Outcomes Research
Background:
- Total artificial heart (TAH) utilization has seen a notable increase in recent years.
- Understanding TAH trends, associated complications, and mortality is crucial for patient care.
Purpose of the Study:
- To evaluate the utilization trends of total artificial hearts in the USA.
- To assess the morbidity and mortality associated with TAH implantation.
Main Methods:
- Analysis of a large nationwide inpatient samples (NIS) database.
- Utilized ICD-9 codes to identify total artificial heart implants.
- Examined device utilization, complications, and mortality rates from 2004 to 2011.
Main Results:
- TAH implantation rates increased from 5 in 2004 to 26 in 2011.
- 22 out of 75 patients (29.3%) experienced mortality.
- Most common complications included acute renal failure (69.3%), infections (28.0%), and bleeding (14.7%).
Conclusions:
- Total artificial heart use in the United States has steadily increased.
- TAH implantation is associated with substantial rates of morbidity and mortality.
Objective:
Total artificial heart (TAH) utilization has increased over the recent years. The goal of this study was to evaluate the trend of artificial hearts used in the USA with its associated morbidity and mortality based on a large in-hospital database.
Materials And Methods:
Using a very large nationwide inpatient samples (NIS) database, we used ICD-9 code for a total artificial heart. We evaluated the utilization of this device over the years studied. Furthermore, we evaluated any associated complications and mortality in patients receiving this device.
Results:
From 2004 until 2011, the rate of total artificial heart implants increased over the years from 5 in 2004 to the highest of 26 in 2011 across the United State. TAH was insesrted in 75 patients. Death was reported in 22 patients (29.3%). Acute renal failure was the most common complication (69.3%). This is followed by post-operative infectious complications (28.0%), acute renal failure requiring dialysis (16%), bleeding complications requiring blood transfusion (14.7%) respiratory complications (6.7%), and stroke/TIA (4.0%). There was no post-operative deep vein thrmobosis or pulmonary embolism.
Conclusions:
The use of total artificial heart has increased in the United State steadily with substantial morbidity and mortality associated with this device.
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