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The Association between Total Genotype Score and Athletic Performance in Weightlifters
Hiroki Homma1, Mika Saito2, Aoto Saito2
1Faculty of Sport Science, Nippon Sport Science University, Tokyo 158-8508, Japan.
Genes
|November 24, 2022
Summary
A newly developed weightlifting-related model (WRM) score showed potential for identifying weightlifters, but did not correlate with performance or apply to other power athletes. Genetic variations influence weightlifting status.
Area of Science:
- Sports Genetics
- Human Performance
- Molecular Biology
Background:
- Genetic polymorphisms are increasingly studied for their association with athletic performance.
- Understanding the genetic basis of power-oriented sports like weightlifting can inform talent identification and training.
Purpose of the Study:
- To investigate the relationship between specific genetic polymorphisms and weightlifting status.
- To develop and validate a Total Genotype Score (TGS) model for power-oriented athletes.
- To assess the applicability of TGS models in weightlifting and other power sports.
Main Methods:
- Genotyping of 12 power-related polymorphisms in 192 weightlifters and 416 controls using TaqMan SNP assay.
- Calculation of a power-oriented whole model (PWM) TGS and a weightlifting-related model (WRM) TGS.
- Comparison of WRM TGS between 177 strength and power athletes and controls.
Main Results:
- No significant difference in PWM TGS between weightlifters and controls.
- Weightlifters and elite weightlifters exhibited higher WRM TGS compared to controls.
- WRM TGS did not correlate with weightlifting performance or show significant differences in other power-oriented athletes.
Conclusions:
- A TGS model (WRM) was successfully developed based on case-control data for weightlifters.
- The developed TGS model demonstrated utility in distinguishing weightlifters but lacked generalizability to broader power-oriented athletic populations.
- Further research is needed to refine genetic models for diverse power sports.
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