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Historical trends in mortality from "older" vaccine-preventable diseases, Colombia: implications for elimination and
C Arango-Úsuga1, J Ochoa1, A León1
1Universidad de Antioquia, Facultad Nacional de Salud Pública, Medellín, Colombia.
Objective:
This study aimed to describe the trends in mortality from eight vaccine-preventable diseases in Colombia in the last 40 years and their relationship with vaccination coverage.
Study Design:
It is a population-based descriptive study.
Methods:
The frequencies of deaths by decade, disease, sex, and the specific mortality rates by age group were calculated. Using a negative binomial regression model, the 10-year changes in mortality and their relationship with vaccination coverage were determined.
Results:
The number of deaths and the adjusted rates decreased since 1989 in all diseases (incidence rate ratio <1 when compared with the 1979-1988 decade). Vaccination coverage below 90% is associated with an increase in mortality from diphtheria, measles, mumps, neonatal tetanus, and pertussis.
Conclusion:
Historical changes in mortality support the benefits of vaccination, but new efforts are required to sustain the elimination of diseases.
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