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Considerations for the use of biomaterials to support cell therapy in neurodegenerative disease
Victoria H Roberton1, James B Phillips1
1UCL School of Pharmacy, University College London, London, United Kingdom; UCL Centre for Nerve Engineering, London, United Kingdom.
Abstract:
Using biomaterials to complement cell therapies for a range of neurodegenerative disorders provides a potential opportunity to improve cell survival, integration and regeneration. Materials can be developed to serve as cell or drug delivery systems, temporary scaffolds or longer-term encapsulation structures. However, as yet clinical translation has been limited, with much work still required to achieve this. This chapter discusses a number of considerations for using biomaterials to support cell therapies, which are likely to be essential to achieve successful translation.
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