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Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
Published on: June 13, 2014
Antitumor pharmacological research in the era of personalized medicine
Min Huang1,2, Mei-Yu Geng1,2, Jian Ding3,4
1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Abstract:
Anticancer drug discovery has yielded unprecedented progress in recent decades, resulting in the approval of innovative treatment options for patients and the successful implementation of personalized medicine in clinical practice. This remarkable progress has also reshaped the research scope of pharmacological research. This article, as a tribute to cancer research at Shanghai Institute of Materia Medica in celebration of the institute's 90th birthday, provides an overview of the conceptual revolution occurring in anticancer therapy, and summarizes our recent progress in the development of molecularly targeted therapeutics and exploration of new strategies in personalized medicine. With this review, we hope to provide a glimpse into how antitumor pharmacological researchers have embraced the new era of personalized medicine research and to propose a future path for anticancer drug discovery and pharmacological research.
Insights
Anticancer drug discovery advances have led to new treatments and personalized medicine. This review highlights progress in molecularly targeted therapeutics and future directions for cancer research.
Area of Science:
- Pharmacological research
- Oncology
- Drug discovery
Background:
- Recent decades show significant progress in anticancer drug discovery.
- Innovative treatments and personalized medicine are now clinical realities.
- This progress has reshaped the landscape of pharmacological research.
Purpose of the Study:
- To provide an overview of the conceptual revolution in anticancer therapy.
- To summarize recent progress in molecularly targeted therapeutics.
- To explore new strategies in personalized medicine for cancer treatment.
Main Methods:
- Review of conceptual advancements in anticancer therapy.
- Summary of recent developments in molecularly targeted drug discovery.
- Exploration of emerging strategies in personalized cancer medicine.
Main Results:
- Anticancer research is embracing a new era of personalized medicine.
- Significant progress has been made in developing molecularly targeted therapeutics.
- New strategies for personalized cancer treatment are being explored.
Conclusions:
- Anticancer drug discovery is rapidly evolving with personalized medicine.
- Molecularly targeted therapeutics represent a key advancement.
- Future research should focus on integrating personalized medicine strategies.
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