Co-infections in Hospitalized COVID-19 Patients- A Prospective Observational Study
Ramniwas Jalandra1, Avinash Babu1, Naveen Dutt1
1Pulmonary Medicine, AII India Institute of Medical Sciences, Jodhpur, IND.
Cureus
|November 25, 2022
Summary
Co-infections in hospitalized COVID-19 patients significantly increase mortality. Urinary tract infections were a common co-infection and an independent risk factor for death, highlighting the need for early detection and treatment.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Epidemiology
Background:
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic declared March 2020.
- Co-infections linked to severe outcomes in past pandemics.
- Limited data on co-infections in COVID-19 patients.
Purpose of the Study:
- Evaluate co-infection prevalence in hospitalized COVID-19 patients.
- Assess the impact of co-infections on morbidity and mortality.
- Identify specific co-infections as risk factors.
Main Methods:
- Prospective observational study.
- 100 patients in a high-dependency unit in India.
- Analysis of co-infection prevalence and clinical outcomes.
Main Results:
- 14% of COVID-19 patients had co-infections.
- Urinary tract infection (UTI) was the most common (9%).
- Co-infections significantly increased mortality (p<0.0004); UTI was an independent risk factor (p<0.001).
Conclusions:
- Co-infections are a significant risk factor for morbidity and mortality in COVID-19.
- Early identification and treatment of co-infections are crucial.
- Improving clinical outcomes through timely management of co-infections.
Related Concept Videos
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.3K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.3K
01:22Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
01:30Pneumonia III: Complications and Assessment
352
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
352
01:26Factors Affecting the Risk of Infection
12.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.2K
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
30
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
30
01:29Pneumonia II: Pathophysiology
423
The pathophysiology of pneumonia involves the following steps:
423