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Peripartum Pharmacotherapy: A Pharmacist's Guide
Kylie N Barnes1, Lauren D Leader2, Nicole E Cieri-Hutcherson3
1Kansas City School of Pharmacy, University of Missouri, Kansas City, MO, USA.
Journal of Pharmacy Practice
|November 25, 2022
Summary
Managing medications during pregnancy and childbirth requires careful attention to maternal and fetal health. Pharmacists play a vital role in ensuring safe and effective pharmacotherapy management throughout the peripartum period.
Area of Science:
- Obstetrics and Gynecology
- Clinical Pharmacy
- Maternal-Fetal Medicine
Background:
- Peripartum complications can stem from pre-existing or pregnancy-induced conditions.
- These complications significantly impact pharmacotherapy management strategies.
Purpose of the Study:
- To highlight the complexities of pharmacotherapy during late pregnancy and delivery.
- To emphasize the importance of pharmacist involvement in postpartum medication management.
Main Methods:
- Review of physiological changes affecting pharmacokinetics during pregnancy.
- Analysis of potential maternal and fetal risks associated with medications.
- Discussion of enhanced monitoring requirements.
Main Results:
- Altered pharmacokinetics and hemodynamics necessitate careful drug selection and dosing.
- Maternal and fetal monitoring are crucial for identifying adverse effects.
- Pharmacist expertise is essential for optimizing medication regimens.
Conclusions:
- Pharmacotherapy in the peripartum period demands meticulous consideration of physiological changes and potential risks.
- Pharmacists are integral to the interprofessional team, providing critical assessments and recommendations for safe medication use.
- Judicious medication management by pharmacists supports improved maternal and fetal outcomes.
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