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Updated: Aug 20, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
NEWS2 and improving outcomes from sepsis
1Hampshire Hospitals NHS Foundation Trust, Winchester, UK; professor, University of Southampton, Southampton, UK; national clinical director for infection, antimicrobial resistance and deterioration and national specialty advisor on sepsis, NHS England; clinical director for digital innovation, Wessex Academic Health Science Network matthew.inada-kim@nhs.net.
Abstract:
The cause of deterioration is often unclear, so it is vitally important that we spot the sick and deteriorating patient from all causes. As a result, warning scores must cater for all conditions, and - where possible - be standardised across all healthcare settings. This article summarises the importance of an 'unblinkered' approach to acute illness assessment, comparing and examining the evidence for different historical scoring systems and looking at the early impact of national alignment to NEWS2 in patients admitted to hospital with suspected bacterial infections.
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