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Related Experiment Video

Updated: Aug 20, 2025

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

[Bladder AA amyloidosis: A rare location. About a case].

Nisrine Hikki¹, Samia Sassi², Naji Reguieg²

¹Service de néphrologie-dialyse-transplantation rénale, CHU Ibn Sina, Rabat, Maroc.

Nephrologie & Therapeutique

|November 25, 2022

Summary

Bladder amyloidosis, a rare condition, can cause severe hematuria. This case highlights bladder AA amyloidosis secondary to Crohn's disease in a renal transplant recipient, emphasizing cause-specific treatment.

Keywords:

Amylose vésicale Bladder amyloidosis Crohn disease Hématurie macroscopique Kidney transplant Macroscopic haematuria Maladie de Crohn Transplantation rénale

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Last Updated: Aug 20, 2025

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Area of Science:

Nephrology
Gastroenterology
Urology

Background:

AA amyloidosis is a rare condition that can manifest in the bladder, leading to significant hematuria.
This case involves a renal transplant patient with a history of Crohn's disease complicated by AA amyloidosis.

Observation:

A 62-year-old male with Crohn's disease and a 20-year history of renal transplant presented with massive hematuria.
Histological examination of a bladder biopsy confirmed AA amyloidosis.
The patient experienced a flare-up of Crohn's disease prior to the hematuria episode.

Findings:

Bladder AA amyloidosis was diagnosed in a renal transplant patient with Crohn's disease.
Massive hematuria was the primary presenting symptom.
Treatment focused on managing the underlying Crohn's disease.

Implications:

Early diagnosis and management of the underlying cause are crucial for treating bladder AA amyloidosis.
Massive hematuria may necessitate urgent interventions, though cystectomy is rarely required.
This case underscores the importance of considering rare complications in patients with chronic inflammatory diseases and organ transplants.