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The Comparison of the Sleep Structure and Sleep Spindle Activity in Children With Primary Snoring and

G Benbir Senel1, M Aktan Suzgun1, C Bibinoglu Amirov2

  • 1Department of Neurology, Sleep and Disorders Unit, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Clinical Pediatrics
|November 26, 2022
PubMed

Insights

Obstructive sleep apnea syndrome (OSAS) in children, not just snoring, significantly reduces sleep spindle density and duration. This finding highlights OSAS as the key factor impacting sleep structure in affected children.

Area of Science:

  • Pediatric Sleep Medicine
  • Neurology
  • Respiratory Medicine

Background:

  • Obstructive sleep apnea syndrome (OSAS) in children alters sleep architecture.
  • The specific impact of snoring on sleep spindle activity remains unclear.

Purpose of the Study:

  • To compare sleep spindle activity in children with primary snoring and/or OSAS versus healthy controls.
  • To determine if snoring or OSAS is the primary driver of changes in sleep spindle activity.

Main Methods:

  • Analysis of polysomnography recordings and sleep spindle activity.
  • Inclusion of 51 children: 8 with primary snoring, 16 with OSAS and snoring, 11 with OSAS without snoring, and 16 healthy controls.

Main Results:

  • Children with OSAS showed significantly decreased sleep spindle density (P = .034) and duration (P = .019) compared to controls.
  • No significant differences in sleep spindle activity were observed between children with primary snoring and healthy controls.
  • Sleep spindle activity did not differ significantly between OSAS with or without snoring.

Conclusions:

  • Obstructive sleep apnea syndrome, rather than snoring itself, negatively affects sleep spindle activity in children.
  • OSAS, irrespective of snoring, warrants greater clinical attention due to its impact on sleep physiology.
  • Different phenotypes of OSAS may involve distinct pathophysiological mechanisms affecting sleep.

Keywords:
childrenobstructive sleep apnea syndromeprimary snoringsleep spindles

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