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Updated: Aug 19, 2025

Assessing Whole-Body Lipid-Handling Capacity in Mice
Published on: November 24, 2020
Dietary and Physiological Factors Affecting Lipid Metabolism and Cardiovascular Risk
1The Jikei University Kashiwa Hospital.
Abstract:
Atherosclerotic cardiovascular disease (ASCVD) is one of the leading causes of death worldwide. The risk of developing CVD is associated with an unhealthy lifestyle. A high level of low-density lipoprotein (LDL) cholesterol (LDL-C) is a primary risk factor for ASCVD. However, even if the LDL-C management target has been achieved, hypertriglyceridemia and a high level of total cholesterol minus high-density lipoprotein (HDL) cholesterol (non-HDL-C), which contains cholesterol concentrations of triglyceride-rich lipoproteins, are considered a significant residual risk factor for ASCVD and consequently the management of these conditions is important for controlling the residual risk for ASCVD.
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