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Objection non-responsive! How maternal immune activation in pregnancy weakens subsequent microglial immune response

Thomas Blank1, Marco Prinz2,3,4

  • 1Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany. thomas.blank@uniklinik-freiburg.de.

Cell Research
|November 29, 2022
PubMed
Abstract

No abstract available in PubMed .

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Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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