Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

142
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
142
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.6K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

6.8K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
6.8K
Bone Disorders01:29

Bone Disorders

3.8K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.8K
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

890
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
890
Respiratory System Abnormal Finding I: Inspection and Percussion01:30

Respiratory System Abnormal Finding I: Inspection and Percussion

374
Respiratory system abnormalities are a significant concern in healthcare due to their potential to indicate underlying severe conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, and pneumonia. These abnormalities can often be detected through physical examination methods like inspection and percussion.
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
374

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of peripheral monocytic myeloid-derived suppressor cells with molecular subtypes in single-center endometrial cancer patients receiving carboplatin + paclitaxel/avelumab (MITO-END3 trial).

Cancer immunology, immunotherapy : CII·2025
Same author

Tezepelumab for severe asthma: elevating current practice to recognize epithelial driven profiles.

Respiratory research·2024
Same author

Body composition and obstructive sleep apnoea assessment in adult patients with Prader-Willi syndrome: a case control study.

Journal of endocrinological investigation·2022
Same author

Cystic lung diseases: radiological aspects.

Clinical radiology·2022
Same author

Diagnostic role of internal mammary lymph node involvement in tuberculous pleurisy: a multicenter study.

Pulmonology·2022
Same author

Diagnostic protocols in oncology: workup and treatment planning. Part 1: the optimitation of CT protocol.

European review for medical and pharmacological sciences·2021
Same journal

The Role of the Nurse in the Management of Irritable Bowel Syndrome: A Narrative Review.

Translational medicine @ UniSa·2025
Same journal

The Time for a Consensus Regarding the Coeliac Disease Diagnosis in Adults has come: Balancing the Pros and Cons of Omitting the Biopsy.

Translational medicine @ UniSa·2025
Same journal

Artificial Intelligence in Interventional Pain Management: Opportunities, Challenges, and Future Directions.

Translational medicine @ UniSa·2025
Same journal

Cross-sectional Study on Medical Attitude Towards Artificial Intelligence Use in Fibromyalgia: Insights From the Annual Thinking Lab on Fibromyalgia Syndrome (ATLAS 2024).

Translational medicine @ UniSa·2025
Same journal

The Association of C-Mill With Traditional Physical Therapy Rehabilitation in a Multiple Sclerosis Patient: A Case Report.

Translational medicine @ UniSa·2025
Same journal

Deep Sedation in High-risk Patients Undergoing Emergency Upper GI Endoscopy: A Retrospective Study Assessing Safety and Effectiveness.

Translational medicine @ UniSa·2025
See all related articles

Related Experiment Video

Updated: Aug 19, 2025

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
07:44

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

10.2K

DPO: Diffuse Pulmonary Ossification - A Diagnostic Challenge.

G Rea1, G Giacobbe2, D Caroppo3

  • 1Dipartimento di Radiologia, Ospedale Monaldi, A.O. dei Colli, Napoli, Italy.

Translational Medicine @ Unisa
|November 30, 2022
PubMed
Summary
This summary is machine-generated.

Diffuse pulmonary ossification (DPO) is a rare lung condition where bone forms in the lungs. This case highlights its potential link to pulmonary fibrosis and interstitial lung disease.

Keywords:
DPODiffuseLungOssificationPulmonary

More Related Videos

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
14:21

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation

Published on: January 22, 2013

14.2K
Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.3K

Related Experiment Videos

Last Updated: Aug 19, 2025

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
07:44

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

10.2K
Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
14:21

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation

Published on: January 22, 2013

14.2K
Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.3K

Area of Science:

  • Pulmonary Medicine
  • Pathology

Background:

  • Diffuse pulmonary ossification (DPO) is a rare diffuse lung disease characterized by ectopic bone formation.
  • It is less common in individuals without pre-existing lung conditions.

Observation:

  • DPO presents as small calcific nodules, often in peripheral lung areas.
  • Two patterns exist: nodular and the less common dendriform, which features a coral-like network of bone spicules along alveolar septa.

Findings:

  • The dendriform pattern is associated with interstitial fibrosis or chronic obstructive lung disease.
  • Recent studies suggest DPO may predict pulmonary fibrosis, correlating with Usual Interstitial Pneumonia (UIP) and Idiopathic Pulmonary Fibrosis (IPF).

Implications:

  • This case report details a 41-year-old male with bronchitis whose chest imaging revealed DPO with a tree-like pattern.
  • Histopathological examination confirmed mature bone tissue in the lung parenchyma, reinforcing DPO's association with fibrotic lung diseases.