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Updated: Aug 19, 2025

The MultiBac Protein Complex Production Platform at the EMBL
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BTB domains: A structural view of evolution, multimerization, and protein-protein interactions

Artem Bonchuk1,2, Konstantin Balagurov1, Pavel Georgiev1

  • 1Department of the Control of Genetic Processes, Institute of Gene Biology Russian Academy of Sciences, Moscow, Russia.

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
|November 30, 2022
PubMed
Summary

The Broad-complex, Tramtrack, and Bric-à-brac/poxvirus and zinc finger (BTB/POZ) domain is crucial for protein interactions in development and cancer. This review updates its classification and discusses structural principles of BTB-mediated interactions.

Keywords:
BTB domainBTB-kelchCullinNPH3TTK groupdimerizationprotein multimerization

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