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Leptospirosis and COVID-19 co-infection case in Bangladesh
Mohammad Ashraful Amin1,2, Sabrina Nahin3, Atia Sharmin Bonna4,2
1Department of Public Health, North South University, Dhaka, 1229, Bangladesh.
Introduction:
Leptospirosis, a zoonotic illness, is comparable to COVID-19 in that the majority of infections are mild or asymptomatic, and only a tiny percentage of those infected experience multiple system affected. Leptospirosis coinfection and the pathogenesis of SARS-CoV-2(Severe Acute Respiratory Syndrome Coronavirus 2) play a significant part in the emergence and progression of SARS-CoV-2 infection by enhancing the difficulty of identification, management, and outcome of COVID-19 well as worsening disease severity and death.
Case Report:
We presented a 47-year-old individual with Leptospirosis diagnosed with SARS-CoV-2. A rapid test for IgM antibodies was used to confirm Leptospirosis. Reverse-transcription Polymerase Chain Reaction was used to establish COVID-19 (RTPCR). During the COVID-19 emergent crisis in Chattogram, Bangladesh, the person was diagnosed and treated with functional, supportive care for COVID-19 and antibiotic therapy for leptospirosis. The patient was given medication and guidance before being discharged from the hospital.To highlight the importance of microbial coinfection in COVID-19, we outline the coinfection of bacteria with SARS-CoV-2, their effects on COVID-19, the grounds for coinfection, and their identification.
Insights
Coinfection with Leptospirosis and COVID-19 (SARS-CoV-2) can worsen disease severity and complicate diagnosis. This case highlights the importance of considering coinfections in patients presenting with COVID-19 symptoms.
Area of Science:
- Infectious Diseases
- Microbiology
- Public Health
Background:
- Leptospirosis and COVID-19 (SARS-CoV-2) are zoonotic diseases with overlapping symptoms, complicating diagnosis.
- Coinfection can exacerbate disease severity and impact patient outcomes.
- Understanding coinfection dynamics is crucial for effective management during pandemics.
Observation:
- A case report details a 47-year-old individual diagnosed with both Leptospirosis and SARS-CoV-2.
- Leptospirosis was confirmed via IgM antibody rapid testing.
- COVID-19 was confirmed using Reverse-transcription Polymerase Chain Reaction (RT-PCR).
Findings:
- The patient received supportive care for COVID-19 and antibiotic therapy for Leptospirosis.
- Coinfection presented diagnostic and management challenges.
- The case underscores the significance of identifying microbial coinfections in COVID-19 patients.
Implications:
- Highlights the need for heightened awareness of coinfections in COVID-19 patients.
- Suggests that prompt diagnosis and treatment of coinfections may improve patient outcomes.
- Emphasizes the importance of considering Leptospirosis in differential diagnoses, especially in endemic areas during the COVID-19 pandemic.
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