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Minimum Allergen Screening Panel for Allergic Rhinitis in Bangalore: A Cross Sectional Study
Rafees Hassan Palliyalthodi1,2, Badari Datta1, Anita Mariet Thomas1
1Department of ENT, Bangalore Baptist Hospital, Hebbal, Bangalore, India.
Summary
A minimum of three allergens, including Dermatophagoides pteronyssinus, Lambs quarter, and Dermatophagoides farinae, can effectively screen over 90% of patients with allergic rhinitis (AR) symptoms. This finding simplifies allergy testing for individuals with AR.
Area of Science:
- Otorhinolaryngology
- Allergology
- Clinical Immunology
Background:
- Allergic rhinitis (AR) is a prevalent condition impacting patient quality of life.
- Current skin prick test (SPT) protocols vary widely in allergen panels used.
- Extensive allergen panels require multiple skin pricks, causing patient discomfort.
Purpose of the Study:
- To identify a minimal allergen panel for screening patients with AR symptoms.
- To establish a cost-effective and efficient SPT protocol.
- To reduce patient burden during allergy testing.
Main Methods:
- Cross-sectional study conducted at an allergy clinic over 18 months.
- 149 patients with AR symptoms undergoing SPT were included.
- Prevalence of sensitization to individual allergens was calculated.
Main Results:
- House dust mites (Dermatophagoides pteronyssinus and Dermatophagoides farinae) were the most common sensitizers.
- Dermatophagoides pteronyssinus sensitized 73.9% of patients.
- Dermatophagoides farinae sensitized 65.8% of patients.
Conclusions:
- A minimum panel of three allergens (Dermatophagoides pteronyssinus, Lambs quarter, Dermatophagoides farinae) identified >90% of sensitized patients.
- This reduced panel can serve as an effective screening tool for AR.
- Optimized allergen panels improve SPT efficiency and patient experience.
