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Updated: Aug 19, 2025

From Voxels to Knowledge: A Practical Guide to the Segmentation of Complex Electron Microscopy 3D-Data
Published on: August 13, 2014
A Computational Complexity Perspective on Segmentation as a Cognitive Subcomputation
Federico Adolfi1,2, Todd Wareham3, Iris van Rooij4,5,6
1Ernst Strüngmann Institute for Neuroscience in Cooperation with Max-Planck Society.
Abstract:
Computational feasibility is a widespread concern that guides the framing and modeling of natural and artificial intelligence. The specification of cognitive system capacities is often shaped by unexamined intuitive assumptions about the search space and complexity of a subcomputation. However, a mistaken intuition might make such initial conceptualizations misleading for what empirical questions appear relevant later on. We undertake here computational-level modeling and complexity analyses of segmentation - a widely hypothesized subcomputation that plays a requisite role in explanations of capacities across domains, such as speech recognition, music cognition, active sensing, event memory, action parsing, and statistical learning - as a case study to show how crucial it is to formally assess these assumptions. We mathematically prove two sets of results regarding computational hardness and search space size that may run counter to intuition, and position their implications with respect to existing views on the subcapacity.
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