Related Experiment Video
Updated: Aug 19, 2025

Murine Kidney Transplant Technique
Published on: October 20, 2015
Simultaneous Renal Transplantation With Bilateral Nephrectomy and Ureterocystoplasty
Omri Nativ1, Pinhas Livne2, Fadi Zu'bi2
1Urology Department, Rambam Medical Center, Haifa, Israel.; Urology Department, Meir Medical Center, Kfar Saba, Israel; Pediatric Surgery Department, Rambam Medical Center, Haifa, Israel.; Vascular surgery Department, HaEmek Hospital, Afula, Israel; General Surgery Department, Rambam Medical Center, Haifa, Israel.; Pediatric Nephrology Department, Rambam Medical Center, Haifa, Israel..
Bladder augmentation may precede kidney transplants in children with end-stage renal disease (ESRD). This case highlights successful simultaneous bilateral nephrectomy, ureterocystoplasty, and renal transplantation for a boy with ESRD, contracted bladder, and reflux.
Area of Science:
- Pediatric Urology
- Nephrology
- Surgical Innovation
Background:
- End-stage renal disease (ESRD) in children often necessitates complex management strategies.
- Bladder augmentation (BA) is sometimes required prior to renal transplantation.
- Posterior urethral valve (PUV) can lead to severe bladder dysfunction and renal damage.
Observation:
- A 7-year-old boy presented with ESRD, a contracted bladder, and severe bilateral reflux due to PUV.
- The patient required intervention before proceeding with renal transplantation.
Findings:
- A successful simultaneous surgical approach was performed.
- This included bilateral nephrectomy, bilateral ureterocystoplasty, and renal transplantation.
- This combined strategy effectively addressed the patient's complex urological and renal issues.
Implications:
- This case demonstrates the feasibility and success of a simultaneous multi-procedure approach in pediatric renal transplantation.
- Such combined interventions can offer a viable solution for complex pediatric ESRD cases with bladder abnormalities.
- This approach may improve outcomes and reduce the number of surgical stages for affected children.
Related Concept Videos
Kidney Transplant II: Surgical Procedure
Kidney Transplant I: Introduction
Kidney Transplant III: Nursing Management
Continuous Renal Replacement Therapy

