Toe Acrometastasis as an Initial Sign of Metastasis in a Patient With a Large Cell Lung Carcinoma
Related Experiment Video
Updated: Aug 19, 2025

Lung Tumor Cell Recruitment Assay
Published on: February 26, 2019
Zakhia Michael Malhame1,2, Rami El Rachkidi3,2
1Department of Orthopaedics and Traumatology, Notre Dame des Secours University Hospital Medical Center, Byblos, LBN.
Abstract:
Acrometastases are rare lesions that originate most commonly from the primary lung cancer. They can mislead the diagnosis and the treatment, since they often appear as an osteomyelitis of the affected area. The presence of these metastases is a sign of poor prognosis, with a life expectancy of few months. We report a case of a 78-year-old male with an acrometastasis to the distal phalanx of the right fourth toe. It was the first sign that his previously diagnosed large cell lung carcinoma had reached a metastatic stage. Amputation of the toe was considered in this case where the intense pain of his acrometastasis could not be managed even with strong analgesics.

