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Demodicosis among immunocompromised patients: a review
Adriana Marquardt-Feszler1, Karolina Cekała1, Alicja Dębska-Ślizień2
1Medical University of Gdansk, Gdansk, Poland.
Postepy Dermatologii I Alergologii
|December 2, 2022
Summary
Immunosuppressed patients may be more prone to demodicosis, a condition caused by Demodex mites. Further research is needed to confirm this link between immunosuppression and Demodex mite infections.
Area of Science:
- Dermatology
- Parasitology
- Immunology
Background:
- Demodex mites (DM) are common human ectoparasites, with Demodex folliculorum and Demodex brevis being the primary species.
- Emerging evidence suggests DM can act as a pathogenic parasite, but patient groups susceptible to demodicosis remain unclear.
Purpose of the Study:
- To conduct a literature review analyzing the potential link between immunosuppression and the development of demodicosis.
Main Methods:
- Literature search primarily conducted on the PubMed database.
- Citation searching of relevant articles was also employed.
Main Results:
- The review included 23 case reports and 13 original works.
- While 4 original works found no correlation, 9 suggested a positive association between demodicosis and immunosuppression.
Conclusions:
- A correlation between demodicosis and immunosuppression appears likely.
- Additional research is required to definitively establish this relationship.
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