Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dysregulated Intraocular Pressure in Acanthamoeba Keratitis: Clinical Associations, Therapy, and Prognosis.

Microorganisms·2026

Same author

Sustainability awareness among European dry eye disease specialists.

European journal of ophthalmology·2026

Same author

Klinische Monatsblatter fur Augenheilkunde·2026

Same author

Corneal Allogeneic Intrastromal Ring Segments (CAIRS): Indications, Mechanism of Action and Outcomes.

Klinische Monatsblatter fur Augenheilkunde·2026

Same author

[Adjuvant Crosslinking to Improve Graft Survival after High-Risk Keratoplasty - A Case Series from the CrossCornealVision Study].

Klinische Monatsblatter fur Augenheilkunde·2026

Same author

Prevalence of anterior corneal scars impairing visual acuity after Descemet membrane endothelial keratoplasty (DMEK) and treatment by phototherapeutic keratectomy (PTK).

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026

Same journal

Current Experimental Methods for Restoration of the Tear Film.

Current eye research·2026

Same journal

Apolipoprotein C3 Promotes Retinal Angiogenesis via the MYC Pathway in Hypoxia.

Current eye research·2026

Same journal

Possible Causal Association Between Thyroid-Related Traits and Diabetic Retinopathy Risk: Evidence From 23 Medication-Taking Traits.

Current eye research·2026

Same journal

Linking Microstructure to Mechanics in ICG-Stained Lens Capsules: Insights from Nanoindentation to Electron Microscopy.

Current eye research·2026

Same journal

Corneal Sensitivity, Sub-Basal Corneal Nerve Plexus, and Tear Neuropeptides in Symptomatic Versus Asymptomatic Visual Display Terminal Users.

Current eye research·2026

Same journal

Selective Laser Trabeculoplasty Mitigates Dexamethasone-Induced Myofibroblast-Like Transformation and Dysfunction in Human Trabecular Meshwork Cells.

Current eye research·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 19, 2025

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

Innovations in Corneal Crosslinking.

Klara Borgardts¹, Johannes Menzel-Severing¹, Isaak Fischinger^2,3,4

¹Department of Ophthalmology, University Hospital Düsseldorf, Düsseldorf, Germany.

Current Eye Research

|December 2, 2022

Summary

This summary is machine-generated.

New Corneal Crosslinking (CXL) protocols enhance keratoconus treatment, offering faster healing and fewer side effects. These advanced methods improve outcomes for progressive keratectasia patients.

Keywords:

CXL PRK customized oxygen riboflavin transepithelial

More Related Videos

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia

Published on: January 6, 2018

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

Related Experiment Videos

Last Updated: Aug 19, 2025

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia

Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia

Published on: January 6, 2018

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

Area of Science:

Ophthalmology
Biomedical Engineering

Background:

Keratoconus is a progressive corneal disease.
Corneal Crosslinking (CXL) is a standard treatment to strengthen the cornea and halt disease progression.

Purpose of the Study:

To review and compare various modified Corneal Crosslinking (CXL) protocols.
To evaluate the efficacy and safety of novel CXL approaches for keratoconus treatment.

Main Methods:

Literature review of PubMed-indexed publications.
Analysis of clinical experiences with different CXL protocols.

Main Results:

Accelerated CXL demonstrates comparable efficacy with reduced surgery time.
Transepithelial CXL in a hyperoxic environment shows promise for reduced complications.
Specialized protocols effectively treat thin corneas and can be combined with PRK for visual rehabilitation.

Conclusions:

Modified CXL protocols offer significant advantages over the standard Dresden protocol.
These advanced techniques should be considered for managing progressive keratectasia.