Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Vaccinations

Vaccinations

Response Surface Methodology

Response Surface Methodology

Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Immunobiological cold chain performance assessment in Brazil: mixed methods research.

BMC health services research·2026

Same author

Spatial distribution of immunization error notifications in the state of Minas Gerais, Brazil.

Ciencia & saude coletiva·2026

Same author

Simulation-based training for teaching infection prevention: from realistic to virtual environments.

Revista brasileira de enfermagem·2025

Same author

Care for ill-housed persons: access and professional proactivity in primary care.

Revista brasileira de enfermagem·2025

Same author

Immunization errors of COVID-19 vaccines in Minas Gerais.

Revista brasileira de enfermagem·2025

Same author

Nursing health technologies in the prevention and control of hepatitis A: a scoping review.

Revista da Escola de Enfermagem da U S P·2025

Same journal

Artificial Intelligence for Assessment and Feedback in Medical Education: Bibliometric Mapping Study and Thematic Evidence Map.

JMIR medical education·2026

Same journal

Digital Simulation-Based Ultrasound Training for Physiotherapy Students: Prospective Randomized Controlled Trial.

JMIR medical education·2026

Same journal

Exploring Ambient Artificial Intelligence to Enhance Learning and Feedback During Operating Room-to-Intensive Care Unit Handoffs: Co-Design and Simulation Study.

JMIR medical education·2026

Same journal

Voice Cloning Using AI vs Traditional Audio Recording for Prerecorded Courses in Medical Pedagogy: Randomized Controlled Trial.

JMIR medical education·2026

Same journal

Parenthood in US Medical Training Across Specialty Groups: Scoping Review.

JMIR medical education·2026

Same journal

User Acceptance of an AI-Powered Medical History-Taking Training System Among Undergraduate Medical Students: Mixed Methods Study.

JMIR medical education·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 19, 2025

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Published on: December 18, 2014

Software-Based Simulation on a 3D Environment for Vaccination Teaching and Learning: Design Science Research.

Daniel Domingueti¹, Darlinton Barbosa Feres Carvalho¹, Diego Roberto Colombo Dias¹

¹Departamento de Ciência da Computação, Universidade Federal de São João del-Rei, Sao Joao del Rei, Brazil.

JMIR Medical Education

|December 2, 2022

Summary

This summary is machine-generated.

A new 3D virtual simulation effectively supports vaccination room training, offering good usability and aiding technology acceptance for nursing students. This innovative tool addresses limitations in traditional training environments.

Keywords:

SUS UTAUT2 Unity3D evaluation immunization software simulation teaching training vaccination room virtual world

More Related Videos

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Published on: November 24, 2021

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

Published on: August 26, 2018

Related Experiment Videos

Last Updated: Aug 19, 2025

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Published on: December 18, 2014

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Published on: November 24, 2021

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

Published on: August 26, 2018

Area of Science:

Medical Education Technology
Virtual Reality in Healthcare Training
Simulation-Based Learning

Background:

Limited access to physical vaccination practice labs hinders student training.
Continuing education for healthcare professionals often lacks adequate resources.
Demand for innovative methodologies like software-based simulations is high.

Purpose of the Study:

To develop a 3D virtual environment for vaccination room teaching activities.
To create a software-based simulation that positively impacts teaching through variable scenarios.

Main Methods:

Design Science Research methodology guided artifact development.
Expert validation via Delphi method and usability testing with nursing students (SUS, UTAUT2).
Development involved a specialist to ensure adherence to Brazilian standards.

Main Results:

A simulation software was developed using the Unity game engine with scenario creation and performance reporting modules.
Expert evaluation deemed the solution adequate; student evaluations showed good usability (SUS score 81.4).
Performance Expectation positively influenced Behavioral Intention; younger users showed higher Effort Expectancy.

Conclusions:

The study successfully created a software-based simulation for vaccination room teaching.
Evaluations indicated high relevance for teaching and identified areas for improvement.
User behavior suggests positive acceptance of this technological artifact in education.