Related Experiment Video
Updated: Aug 19, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Segmental mandibular advancement for moderate-to-severe obstructive sleep apnoea: a pilot study
Y Y Leung1, J C C Wan1, H L Fu1
1Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong.
Segmental mandibular advancement (SMA) surgery significantly improved breathing in obstructive sleep apnoea (OSA) patients. This surgical technique for moderate-to-severe OSA demonstrated high success rates and minimal complications.
Area of Science:
- Oral and Maxillofacial Surgery
- Sleep Medicine
- Respiratory Medicine
Background:
- Obstructive sleep apnoea (OSA) is a common respiratory disorder characterized by repeated episodes of airway obstruction during sleep.
- Moderate-to-severe OSA often requires advanced treatment strategies, including surgical interventions to address tongue base obstruction.
- Segmental mandibular advancement (SMA) is a surgical technique designed for significant mandibular advancement to improve airway patency.
Purpose of the Study:
- To evaluate the surgical outcomes and complication rates of Segmental mandibular advancement (SMA) in patients with moderate-to-severe obstructive sleep apnoea (OSA).
- To assess the efficacy of SMA in improving respiratory parameters and airway dimensions in OSA patients.
Main Methods:
- A pilot study involving twelve patients (nine male, three female) diagnosed with moderate-to-severe OSA.
- Patients underwent Segmental mandibular advancement (SMA) as part or the entirety of their skeletal advancement procedure.
- Surgical outcomes were assessed by monitoring the apnoea-hypopnoea index (AHI), lowest oxygen saturation (LSAT), and airway volume changes one year postoperatively.
Main Results:
- The apnoea-hypopnoea index (AHI) decreased from a mean of 42.4/hour preoperatively to 9.0/hour at one year postoperative.
- Surgical success, defined as a 50% reduction in AHI, was achieved in 91.7% of patients, with 58.3% achieving surgical cure (AHI<5/hour).
- Airway volume significantly increased from 2.4 cm³ to 6.7 cm³ (P < 0.001), and lowest oxygen saturation improved from 73.3% to 78.7%.
Conclusions:
- Segmental mandibular advancement (SMA) appears to be a safe and effective surgical option for managing moderate-to-severe obstructive sleep apnoea (OSA).
- The procedure leads to significant improvements in respiratory function and airway dimensions with a low incidence of major complications.
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Cardiopulmonary Resuscitation II: ACLS Airway Management
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

