Related Experiment Video
Updated: Aug 19, 2025
08:45
Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
13.8K
Antifungal stewardship: What we need to know
Arunima Ray1, Anupam Das2, Saumya Panda3
1Department of Dermatology, Christian Medical College, Vellore, Tamil Nadu, India.
Indian Journal of Dermatology, Venereology and Leprology
|December 3, 2022
Summary
Antifungal stewardship programs are crucial for combating rising drug resistance and treatment failures. Implementing these programs ensures rational use of antifungals, improving patient outcomes.
Area of Science:
- * Infectious Diseases and Pharmacology
- * Antimicrobial Resistance and Stewardship
Background:
- * Growing resistance to established antifungal therapies is a significant global health concern.
- * Irrational and unscientific prescription patterns contribute to the escalating problem of antifungal resistance.
- * Treatment failures are increasingly reported due to widespread antifungal resistance.
Purpose of the Study:
- * To summarize the fundamental concepts of antifungal stewardship programs.
- * To highlight the urgent necessity for implementing antifungal stewardship.
- * To address the current challenges posed by antifungal resistance and treatment failures.
Main Methods:
- * A comprehensive literature search was conducted across major scientific databases (PubMed, EMBASE, MEDLINE, Cochrane).
- * The search focused on English language publications from 1990 to 2022.
- * Review of existing reports on antifungal resistance and stewardship initiatives.
Main Results:
- * Extensive literature confirms a substantial increase in resistance to existing antifungal drugs.
- * Evidence indicates widespread irrational prescribing of antifungal agents.
- * Antifungal stewardship has emerged as a critical area of focus in response to these trends.
Conclusions:
- * Antifungal stewardship is essential to combat rising resistance and improve therapeutic efficacy.
- * Implementing structured stewardship programs is vital for rational antifungal use.
- * Addressing antifungal resistance requires a coordinated approach through stewardship initiatives.
Related Concept Videos
01:26Standard Precaution
2.1K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
2.1K
01:22Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
01:28Antimicrobial Effectiveness
130
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
130
01:23Hand hygiene
3.5K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.5K
01:29Key Techniques in Microbiology
210
Aseptic techniques prevent contamination, ensure experimental accuracy, and protect researchers and microbial cultures. These techniques are essential in clinical, industrial, and research settings where sterility is required.Maintaining Sterility in Laboratory PracticesScientists maintain sterility by sterilizing tools with heat or chemicals, disinfecting work surfaces, and handling cultures in controlled environments. Working near an open flame or within a laminar flow hood reduces the risk...
210
01:18Endocarditis III: Medical Management
11
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
11