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Updated: Aug 19, 2025

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments
Published on: March 1, 2022
Semantic coherence markers: The contribution of perplexity metrics
Davide Colla1, Matteo Delsanto1, Marco Agosto2
1University of Turin, Computer Science Department, Italy.
Language models can detect mental health conditions by analyzing text. Perplexity scores accurately differentiate between healthy individuals and those with Alzheimer
Area of Science:
- Computational linguistics
- Psychiatric diagnostics
- Artificial intelligence in healthcare
Background:
- Early detection of mental disturbances and psychotic disorders is a significant challenge.
- Language models offer a novel approach to analyzing linguistic patterns for diagnostic support.
Purpose of the Study:
- To investigate the utility of language models and perplexity scores for analyzing individual language characteristics.
- To determine if perplexity can discriminate between healthy subjects and those with Alzheimer Disease (AD).
Main Methods:
- Utilized various language models, including N-grams (2- to 5-grams) and GPT-2.
- Assessed perplexity scores across different linguistic registers and subject groups.
- Conducted experiments to differentiate between transcripts of healthy subjects and AD patients.
Main Results:
- Perplexity scores demonstrated stability and consistency across different language models and individual subjects.
- Scores were sensitive to variations in linguistic registers within the same speaker.
- Models achieved perfect accuracy (1.00) in classifying subjects with and without Alzheimer Disease.
Conclusions:
- Perplexity is a reliable metric for analyzing individual language and detecting linguistic anomalies.
- Perplexity analysis using language models shows significant potential for supporting the early diagnosis of mental disorders like AD.
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