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Updated: Aug 19, 2025

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Published on: April 7, 2015
Infective Endocarditis From Pseudomonas aeruginosa and Group C Streptococcus
Abhinandan R Chittal1, Shiavax J Rao1, Pallavi Lakra1
1Internal Medicine, MedStar Union Memorial Hospital, Baltimore, USA.
Endocarditis, an infection of the heart lining, can be caused by various pathogens. This case highlights a severe multi-bacterial infection involving Pseudomonas aeruginosa and Streptococcus in a patient with a history of substance abuse.
Area of Science:
- Infectious Diseases
- Cardiology
- Internal Medicine
Background:
- Endocarditis is inflammation of the heart's inner lining, often caused by infection.
- Commonly affects intravenous drug users, those with catheters, or after invasive procedures.
- Pathogens vary based on risk factors, local epidemiology, and prevalent bacteria.
Observation:
- A patient with a history of polysubstance abuse and prior endocarditis presented with recurrent bacteremia.
- Developed a complex, multi-bacterial infection involving Pseudomonas aeruginosa and group C Streptococcus.
- The infection affected both the right and left sides of the heart.
Findings:
- The case illustrates a rare instance of dual infection with P. aeruginosa and group C Streptococcus.
- Demonstrates the potential for severe cardiac involvement in immunocompromised or high-risk patients.
- Highlights the challenges in managing polymicrobial endocarditis.
Implications:
- Reviews common presentations of bacterial endocarditis.
- Discusses medical and surgical management strategies for endocarditis.
- Emphasizes the importance of considering polymicrobial infections in at-risk populations.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Rheumatic Heart Disease I: Introduction
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.

