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Visceral adiposity indices and cardiometabolic risk markers in patients with hypertension

Berilany Dos Santos Sena1, Fabiana Cristina Lima da Silva Pastich Gonçalves2, Regiane Maio2

  • 1Programa de Pós-graduação em Nutrição, Universidade Federal de Pernambuco, Recife, PE, Brasil, berilanysena@outlook.com.

Archives of Endocrinology and Metabolism
|December 5, 2022
PubMed

Insights

Visceral adiposity index (VAI) and lipid accumulation product (LAP) are linked to higher cardiometabolic risk in hypertension patients. These adiposity markers may help screen for cardiovascular disease (CVD) risk.

Area of Science:

  • Cardiology
  • Endocrinology
  • Metabolic Syndrome

Background:

  • Arterial hypertension (AH) is a significant risk factor for cardiovascular diseases (CVD).
  • Assessing cardiometabolic risk in hypertensive patients is crucial for CVD prevention.
  • Traditional risk factors may not fully capture the complex interplay of adiposity and metabolic health.

Purpose of the Study:

  • To evaluate the association between visceral adiposity index (VAI) and lipid accumulation product (LAP) with cardiometabolic risk markers in patients with arterial hypertension.
  • To determine if VAI and LAP can serve as screening tools for CVD risk in hypertensive individuals.

Main Methods:

  • Cross-sectional study involving 1,273 hypertensive outpatients.
  • Calculation of VAI and LAP using sex-stratified formulas.
  • Assessment of cardiometabolic risk variables including BMI, waist circumference, WHR, WHA, and biochemical parameters.
  • Multivariate linear regression analysis to determine predictive effects.

Main Results:

  • Higher cardiometabolic risk (based on BMI, WHR, WHA, and biochemical parameters) was significantly associated with elevated VAI and LAP values (p ≤ 0.05).
  • Multivariate regression models explained 30.7% of the variance in LAP and 10.5% in VAI.
  • These findings indicate a strong correlation between these adiposity indices and established cardiometabolic risk factors.

Conclusions:

  • Lipid accumulation product (LAP) and visceral adiposity index (VAI) are significantly associated with cardiometabolic risk parameters in hypertensive patients.
  • VAI and LAP demonstrate potential as valuable screening tools for identifying individuals with increased CVD risk among those with AH.
  • Further research can explore the clinical utility of these indices in risk stratification and management strategies for hypertension.
Abstract

Keywords:
Adipositycardiovascular diseaseshypertensionnutritional status

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