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Short-Term Complications After Total Thyroidectomy in Children

Audra J Reiter1, Andrew Hu1, Gwyneth A Sullivan1

  • 1Northwestern Quality Improvement, Research, and Education in Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Division of Pediatric Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois.

The Journal of Surgical Research
|December 5, 2022
PubMed

Insights

Total thyroidectomy in children is safe for both benign and malignant conditions, showing similar low complication rates. Further research is needed to understand long-term outcomes after pediatric thyroid surgery.

Area of Science:

  • Pediatric surgery
  • Endocrinology
  • Surgical oncology

Background:

  • Total thyroidectomy for benign conditions is increasingly performed in pediatric patients.
  • Understanding short-term outcomes is crucial for evaluating surgical safety in children.

Purpose of the Study:

  • To evaluate 30-day postoperative outcomes in children undergoing total thyroidectomy.
  • To compare short-term outcomes between pediatric patients with benign versus malignant indications for total thyroidectomy.

Main Methods:

  • Retrospective cohort study utilizing the American College of Surgeons National Surgical Quality Improvement Program-Pediatric (NSQIP-Pediatric) database (2015-2019).
  • Fisher's exact test was employed to compare postoperative outcomes between benign and malignant surgical indications.

Main Results:

  • The study included 1595 pediatric patients: 1091 (68.4%) with benign and 504 (31.6%) with malignant indications.
  • Overall complication rates were low and similar between benign (2.8%) and malignant (4.6%) cohorts.
  • Key outcomes such as length of stay, parathyroid auto-transplantation rates, readmissions, and reoperations did not significantly differ between the two groups.

Conclusions:

  • Pediatric total thyroidectomy demonstrates low 30-day postoperative complication rates for both benign and malignant indications.
  • The findings support total thyroidectomy as a safe surgical option for children with benign thyroid disease.
  • Further investigation into the long-term outcomes following pediatric total thyroidectomy is warranted.
Abstract

Keywords:
Pediatric surgeryPostoperative complicationsThyroid diseaseTotal thyroidectomy

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