Circularly Polarized Luminescent Eu₄(L)₄ Cage for Enantiomeric Excess and Concentration Simultaneous Determination of...

Undoubtably, it is challenging to simultaneously determine the identity, enantiomeric excess (ee), and total concentration of an enantiomer by just one optical measurement. Herein, we design a chiral tetrahedron Eu₄(L)₄ with circularly polarized luminescence (CPL), which presents highly selective/stereoselective, rapid, and "turn-on" CPL response to chiral diamines, rather than the monoamino compounds, such as monoamines or amino alcohols. By recording the left- and right-CPL intensities of the Eu³⁺ ion at 591 nm, the enantiomeric composition and concentration of chiral diamines can be simultaneously determined by monitoring the g_lum value and total emission intensity (I_L + I_R), respectively. Spectroscopy analyses demonstrate that the variations of g_lum depend on the inversion and maintenance of configuration around the Eu³⁺ ion (Δ ↔ Λ), while the "turn-on" response arises from the raising of the T₁ state of the ligand. The molecule/electron structural variations are proposed from the synergetic supramolecular interactions of NH₂ groups with pendant diols and trifluoroacetyl groups.