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Longitudinal Virological and Immunological Profile in a Case of Human Monkeypox Infection

Maria Antonella Zingaropoli1, Alberico Parente1, Blerta Kertusha2

  • 1Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.

Open Forum Infectious Diseases
|December 7, 2022
PubMed

Keywords:
MPXVNK cellsflow cytometryimmunophenotypingproctitis

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Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.