[The Application of RNA-Sequencing in Pediatric B-Cell Acute Lymphoblastic Leukemia]

Pin-Li Zou1, Xin Liao2, Jian-Wen Xiao3

  • 1Neonatal Intensive Care Unit, Chengdu Women's and Children's Central Hospital, Chengdu 610091, Sichuan Province, China,Department of Hematology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.

Summary

RNA-sequencing (RNA-seq) effectively identifies known and novel gene fusions and mutations in pediatric B-cell acute lymphoblastic leukemia (B-ALL). This molecular profiling aids in risk stratification and targeted therapy for improved patient outcomes.