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[The Application of RNA-Sequencing in Pediatric B-Cell Acute Lymphoblastic Leukemia]
Pin-Li Zou1, Xin Liao2, Jian-Wen Xiao3
1Neonatal Intensive Care Unit, Chengdu Women's and Children's Central Hospital, Chengdu 610091, Sichuan Province, China,Department of Hematology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
|December 8, 2022
Summary
RNA-sequencing (RNA-seq) effectively identifies known and novel gene fusions and mutations in pediatric B-cell acute lymphoblastic leukemia (B-ALL). This molecular profiling aids in risk stratification and targeted therapy for improved patient outcomes.
Area of Science:
- Molecular biology
- Pediatric oncology
- Genetics
Keywords:
B-cell acute lymphoblastic leukemiaRNA-sequencingchildrenfusion genenext generation sequencing
