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Iron deficiency anemia in infants in Sousa (PB), Brazil: an association with nutritional status
Luênnia Kerlly Alves Rocha de Araújo1, João Carlos Pina Faria1,2, Roseli Oselka Saccardo Sarni1,3
1Centro Universitário Faculdade de Medicina do ABC, Departamento de Pediatria - Santo André (SP), Brasil.
Insights
High rates of anemia and iron deficiency anemia (IDA) were found in infants, with iron deficiency linked to poorer weight-for-height, highlighting infant nutritional vulnerability.
Area of Science:
- Pediatric Nutrition
- Hematology
- Public Health
Background:
- Anemia and iron deficiency anemia (IDA) are significant global health concerns in infants.
- Nutritional status is crucial for infant development, especially during the introduction of complementary feeding.
Purpose of the Study:
- To determine the prevalence of anemia and IDA in infants aged 7-9 months.
- To investigate the relationship between iron deficiency and infant nutritional status.
Main Methods:
- A cross-sectional study involving 104 infants (7-9 months) in Brazil.
- Data collection included clinical, anthropometric measurements, and 24-hour dietary recall using DietPro software.
- Statistical analysis involved multiple logistic regression to identify factors associated with iron deficiency.
Main Results:
- Anemia prevalence was 40.4%, and IDA prevalence was 19.2%.
- Infants with IDA showed lower hemoglobin and ferritin levels and increased Z-scores for BMI-for-age, weight-for-height, and weight-for-age.
- Iron deficiency was significantly associated with a higher weight-for-height Z-score (OR: 2.86).
Conclusions:
- Approximately 60% of infants exhibited anemia or IDA.
- Iron deficiency is linked to altered anthropometric indicators, emphasizing infant vulnerability during complementary feeding.
- Findings underscore the need for monitoring and intervention strategies for infant iron status.
Objective:
The aim of this study was to describe the prevalence of anemia and iron deficiency anemia (IDA) in infants and verify the association of iron deficiency with nutritional status.
Methods:
This cross-sectional and observational study included 104 infants aged between 7 and 9 months, assisted from August to September 2021 by the Family Health Strategy program in Sousa municipality (Paraíba, Brazil). Clinical and anthropometric data were collected, and a 24-h food recall questionnaire was applied using the DietPro software (version 5.0) in order to verify food consumption and assess iron intake. Variables associated with iron deficiency (p<0.05) were analyzed using multiple logistic regression.
Results:
Anemia and IDA were observed in 40.4% and 19.2% of infants, respectively. Only one infant was taking prophylactic supplementation (ferrous sulfate). Infants with IDA presented reduced hemoglobin (p<0.001) and ferritin (p<0.001) and increased Z-scores of body mass index-for-age (Z-BMI) (p=0.027), weight-for-height (p=0.007), and weight-for-age (p=0.032). All Z-scores were inversely correlated with ferritin (Z-BMI [rho: -0.37; p<0.001], weight-for-height [rho: -0.37; p<0.001], and weight-for-age [rho: -0.29; p=0.002]). Ferritin was also directly correlated with daily iron intake (rho: 0.22; p=0.018). Finally, multiple logistic regression showed a significant and direct association of iron deficiency with weight-for-height Z-score (odds ratio: 2.86; 95% confidence interval: 1.38-5.64; p=0.004).
Conclusion:
About 60% of infants presented anemia or IDA. Iron deficiency was associated with the weight-for-height Z-score, showing the vulnerability of infants during the introduction of complementary feeding.
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