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Society of Interventional Radiology (SIR) 2026 Practice Guidance Document for Prostatic Artery Embolization.

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Prostatic artery embolization using reflux-control microcatheter: prospective experience addressing feasibility.

André Moreira de Assis1, Willian Yoshinori Kawakami2, Airton Mota Moreira2

  • 1Interventional Radiology Department, Radiology Institute, University of Sao Paulo Medical School, Dr. Enéas de Carvalho Aguiar Avenue, 255, Cerqueira César, São Paulo, 05403-000, Brazil. andre.assis@criep.com.br.

CVIR Endovascular
|December 8, 2022
PubMed
Summary

Prostatic Artery Embolization (PAE) effectively treated lower urinary tract symptoms (LUTS) in benign prostate hyperplasia (BPH) patients. This minimally invasive procedure showed significant symptom improvement and prostate volume reduction with a good safety profile.

Keywords:
Benign prostatic hyperplasiaLower urinary tract symptomsNon-target embolizationProstate artery embolization

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Area of Science:

  • Interventional Radiology
  • Urology
  • Medical Device Technology

Background:

  • Benign prostate hyperplasia (BPH) is a common condition causing lower urinary tract symptoms (LUTS).
  • Traditional treatments for BPH can have significant side effects.
  • Prostatic Artery Embolization (PAE) offers a minimally invasive alternative for BPH management.

Purpose of the Study:

  • To evaluate the efficacy and safety of Prostatic Artery Embolization (PAE).
  • To assess the use of a reflux control microcatheter in PAE procedures.
  • To determine the impact of PAE on LUTS and prostate parameters in BPH patients.

Main Methods:

  • Prospective, single-center study involving 10 patients with BPH-related LUTS.
  • PAE performed using a reflux control microcatheter.
  • Efficacy assessed at baseline, 3, and 12 months via PSA, uroflowmetry, MRI, IPSS, and QoL scores.
  • Complications classified using the Cirse system.

Main Results:

  • Significant 12-month improvements in IPSS (-86.6%) and QoL (-79.4%).
  • Mean prostate volume decreased by 38.4% and PSA by 50.1%.
  • Peak urinary flow (Qmax) increased by 199.4%; one patient required TURP, and one microcatheter replacement occurred.

Conclusions:

  • PAE using a reflux control microcatheter is a safe and effective treatment for LUTS in BPH.
  • The procedure demonstrated significant improvements in urinary symptoms and prostate size.
  • This technique shows promise as a viable therapeutic option for BPH.