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[A case of acute exudative polymorphous vitelliform maculopathy].

J Zhang¹, S L Zhang¹, Y Y Ma¹

¹Department of Ophthalmology of the Affiliated Hospital of Yunnan University, Yunnan Eye Hospital, Yunnan Institute of Ophthalmology, Yunnan Key Laboratory of Ophthalmic Disease Prevention and Treatment, Yunnan Clinical Medical Center for Ophthalmic Diseases, Yunnan Clinical Medical Research Center for Eye Diseases, Kunming 650021, China.

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology

|December 8, 2022

Summary

This case study highlights acute exudative polymorphous vitelliform maculopathy, a rare condition causing blurred vision. Despite initial presentation, the condition worsened without specific treatment, indicating a need for further investigation.

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Area of Science:

Ophthalmology
Medical Imaging
Retinal Diseases

Background:

Acute exudative polymorphous vitelliform maculopathy (AEPVM) is a rare condition characterized by distinct macular findings.
Early diagnosis and understanding of AEPVM progression are crucial for patient management.

Observation:

A 35-year-old male presented with bilateral blurred vision and multiple yellow-white punctate lesions in the posterior pole.
Ocular multimodal imaging revealed cystoid macular edema, submacular edema, ellipsoid zone thickening, and enhanced macular reflex.
Fundus autofluorescence showed hyperautofluorescence, while fluorescein angiography demonstrated no leakage.

Findings:

The patient was diagnosed with AEPVM based on clinical presentation and multimodal imaging.
Despite no specific treatment, the patient experienced lesion fusion, expansion, and worsening macular edema within one week.

Implications:

This case underscores the potential for rapid progression in AEPVM, even without immediate intervention.
Further research into the pathophysiology and optimal treatment strategies for AEPVM is warranted.
Multimodal imaging plays a critical role in the diagnosis and monitoring of AEPVM.